Van Lanen, Steven G.: search on Z-Library

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1

Nature’s combinatorial biosynthesis and recently engineered production of nucleoside antibiotics inStreptomyces

Chen, Shawn, Kinney, William A., Van Lanen, Steven

Journal:

World Journal of Microbiology and Biotechnology

Year:

2017

Language:

english

File:

PDF, 903 KB

english, 2017

2

Identification of the biosynthetic gene cluster of A-500359s in Streptomyces griseus SANK60196

Funabashi, Masanori, Nonaka, Koichi, Yada, Chieko, Hosobuchi, Masahiko, Masuda, Nobuhisa, Shibata, Tomoyuki, Van Lanen, Steven G

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 320 KB

english, 2009

3

The Role of a Nonribosomal Peptide Synthetase in l -Lysine Lactamization During Capuramycin Biosynthesis

Liu, Xiaodong, Jin, Yuanyuan, Cui, Zheng, Nonaka, Koichi, Baba, Satoshi, Funabashi, Masanori, Yang, Zhaoyong, Van Lanen, Steven G.

Journal:

Year:

2016

Language:

english

File:

PDF, 971 KB

english, 2016

4

Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S -Adenosyl- L -Methionine Analogues

Singh, Shanteri, Zhang, Jianjun, Huber, Tyler D., Sunkara, Manjula, Hurley, Katherine, Goff, Randal D., Wang, Guojun, Zhang, Wen, Liu, Chunming, Rohr, Jürgen, Van Lanen, Steven G., Morris, Andrew J.,

Journal:

Angewandte Chemie

Year:

2014

Language:

english

File:

PDF, 978 KB

english, 2014

5

The Biosynthesis of Liposidomycin-like A-90289 Antibiotics Featuring a New Type of Sulfotransferase

Masanori Funabashi, Satoshi Baba, Koichi Nonaka, Masahiko Hosobuchi, Yoko Fujita, Tomoyuki Shibata, Steven G. Van Lanen

Journal:

Year:

2010

Language:

english

File:

PDF, 392 KB

english, 2010

6

The Neocarzinostatin Biosynthetic Gene Cluster from Streptomyces carzinostaticus ATCC 15944 Involving Two Iterative Type I Polyketide Synthases

Wen Liu, Koichi Nonaka, Liping Nie, Jian Zhang, Steven D. Christenson, Juyun Bae, Steven G. Van Lanen, Emmanuel Zazopoulos, Chris M. Farnet, Catherine F. Yang, Ben Shen

Journal:

Chemistry & Biology

Year:

2005

Language:

english

File:

PDF, 395 KB

english, 2005

7

Substrate Specificity of the Adenylation Enzyme SgcC1 Involved in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027

Van Lanen, Steven G., Lin, Shuangjun, Dorrestein, Pieter C., Kelleher, Neil L., Shen, Ben

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 852 KB

english, 2006

8

Refining and expanding nonribosomal peptide synthetase function and mechanism

McErlean, Matt, Overbay, Jonathan, Van Lanen, Steven

Journal:

Journal of Industrial Microbiology & Biotechnology

Year:

2019

Language:

english

File:

PDF, 1.81 MB

english, 2019

9

Progress in combinatorial biosynthesis for drug discovery

Steven G. Van Lanen, Ben Shen

Journal:

Drug Discovery Today: Technologies

Year:

2006

Language:

english

File:

PDF, 590 KB

english, 2006

10

Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471

Cui, Zheng, Wang, Xiachang, Koppermann, Stefan, Thorson, Jon S., Ducho, Christian, Van Lanen, Steven G.

Journal:

Journal of Natural Products

Year:

2018

Language:

english

File:

PDF, 1.87 MB

english, 2018

11

Pyridoxal-5â²-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis

Cui, Zheng, Overbay, Jonathan, Wang, Xiachang, Liu, Xiaodong, Zhang, Yinan, Bhardwaj, Minakshi, Lemke, Anke, Wiegmann, Daniel, Niro, Giuliana, Thorson, Jon S., Ducho, Christian, Van Lanen, Steven G.

Journal:

Nature Chemical Biology

Year:

2020

File:

PDF, 1.60 MB

2020

12

The Bifunctional Glyceryl Transferase/Phosphatase OzmB Belonging to the HAD Superfamily That Diverts 1,3-Bisphosphoglycerate into Polyketide Biosynthesis

Dorrestein, Pieter C., Van Lanen, Steven G., Li, Wenli, Zhao, Chunhua, Deng, Zixin, Shen, Ben, Kelleher, Neil L.

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 96 KB

english, 2006

13

A branch point of Streptomyces sulfur amino acid metabolism controls the production of albomycin

Kulkarni, Aditya, Zeng, Yu, Zhou, Wei, Van Lanen, Steven, Zhang, Weiwen, Chen, Shawn

Journal:

Applied and Environmental Microbiology

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

14

Biosynthesis: SAM cycles up for colibactin

Van Lanen, Steven G

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 432 KB

english, 2017

15

Computer-aided drug design of capuramycin analogues as anti-tuberculosis antibiotics by 3D-QSAR and molecular docking

Jin, Yuanyuan, Fan, Shuai, Lv, Guangxin, Meng, Haoyi, Sun, Zhengyang, Jiang, Wei, Van Lanen, Steven G., Yang, Zhaoyong

Journal:

Language:

english

File:

PDF, 1.91 MB

english

16

Self-Resistance During Muraymycin Biosynthesis: A Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order

Cui, Zheng, Wang, Xia-Chang, Liu, Xiaodong, Lemke, Anke, Koppermann, Stefan, Ducho, Christian, Rohr, Jürgen, Thorson, Jon S., Van Lanen, Steven G.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2018

Language:

english

File:

PDF, 1.45 MB

english, 2018

17

Characterization of SgcE6, the flavin reductase component supporting FAD-dependent halogenation and hydroxylation in the biosynthesis of the enediyne antitumor antibiotic C-1027

Steven G. Van Lanen, Shuangjun Lin, Geoff P. Horsman, Ben Shen

Journal:

FEMS Microbiology Letters

Year:

2009

Language:

english

File:

PDF, 306 KB

english, 2009

18

Kinetic Mechanism of the tRNA-Modifying Enzyme S -Adenosylmethionine:tRNA Ribosyltransferase-Isomerase (QueA) †

Van Lanen, Steven G., Iwata-Reuyl, Dirk

Journal:

Year:

2003

Language:

english

File:

PDF, 176 KB

english, 2003

19

Biosynthesis of Enediyne Antitumor Antibiotics

Van Lanen, Steven, Shen, Ben

Journal:

Current Topics in Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 623 KB

english, 2008

20

Enzymatic Total Synthesis of Defucogilvocarcin M and Its Implications for Gilvocarcin Biosynthesis

Dr. Pallab Pahari, Prof. Dr. Madan K. Kharel, Dr. Micah D. Shepherd, Prof. Dr. Steven G. van Lanen, Prof. Dr. Jürgen Rohr

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 358 KB

english, 2012

21

Structure-Based Gene Targeting Discovery of Sphaerimicin, a Bacterial Translocase I Inhibitor

Funabashi, Masanori, Baba, Satoshi, Takatsu, Toshio, Kizuka, Masaaki, Ohata, Yasuo, Tanaka, Masahiro, Nonaka, Koichi, Spork, Anatol P., Ducho, Christian, Chen, Wei-Chen Leyla, Van Lanen, Steven G.

Journal:

Angewandte Chemie International Edition

Year:

2013

Language:

english

File:

PDF, 858 KB

english, 2013

22

Microbial genomics for the improvement of natural product discovery

Steven G Van Lanen, Ben Shen

Journal:

Current Opinion in Microbiology

Year:

2006

Language:

english

File:

PDF, 434 KB

english, 2006

23

Structure-Based Gene Targeting Discovery of Sphaerimicin, a Bacterial Translocase I Inhibitor

Funabashi, Masanori, Baba, Satoshi, Takatsu, Toshio, Kizuka, Masaaki, Ohata, Yasuo, Tanaka, Masahiro, Nonaka, Koichi, Spork, Anatol P., Ducho, Christian, Chen, Wei-Chen Leyla, Van Lanen, Steven G.

Journal:

Angewandte Chemie

Year:

2013

Language:

english

File:

PDF, 817 KB

english, 2013

24

Cover Feature: Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics (ChemMedChem 8/2018)

Koppermann, Stefan, Cui, Zheng, Fischer, Patrick D., Wang, Xiachang, Ludwig, Jannine, Thorson, Jon S., Van Lanen, Steven G., Ducho, Christian

Journal:

Year:

2018

File:

PDF, 1.03 MB

2018

25

Characterization of NcsB2 as a Promiscuous Naphthoic Acid/Coenzyme A Ligase Integral to the Biosynthesis of the Enediyne Antitumor Antibiotic Neocarzinostatin

Cooke, Heather A., Zhang, Jian, Griffin, Meghan A., Nonaka, Koichi, Van Lanen, Steven G., Shen, Ben, Bruner, Steven D.

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 97 KB

english, 2007

26

Biosynthesis of Albomycin δ 2 Provides a Template for Assembling Siderophore and Aminoacyl-tRNA Synthetase Inhibitor Conjugates

Zeng, Yu, Kulkarni, Aditya, Yang, Zhaoyong, Patil, Preeti B., Zhou, Wei, Chi, Xiuling, Van Lanen, Steven, Chen, Shawn

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 571 KB

english, 2012

27

Amalgamation of Nucleosides and Amino Acids in Antibiotic Biosynthesis: Discovery of an l -Threonine:Uridine-5′-Aldehyde Transaldolase

Barnard-Britson, Sandra, Chi, Xiuling, Nonaka, Koichi, Spork, Anatol P., Tibrewal, Nidhi, Goswami, Anwesha, Pahari, Pallab, Ducho, Christian, Rohr, Jurgen, Van Lanen, Steven G.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 1.34 MB

english, 2012

28

An ATP-independent strategy for amide bond formation in antibiotic biosynthesis

Funabashi, Masanori, Yang, Zhaoyong, Nonaka, Koichi, Hosobuchi, Masahiko, Fujita, Yoko, Shibata, Tomoyuki, Chi, Xiuling, Van Lanen, Steven G

Journal:

Nature Chemical Biology

Year:

2010

Language:

english

File:

PDF, 468 KB

english, 2010

29

Biosynthetic Origin and Mechanism of Formation of the Aminoribosyl Moiety of Peptidyl Nucleoside Antibiotics

Chi, Xiuling, Pahari, Pallab, Nonaka, Koichi, Van Lanen, Steven G.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 2.08 MB

english, 2011

30

Delineating the earliest steps of gilvocarcin biosynthesis: role of GilP and GilQ in starter unit specificity

Shepherd, Micah D., Kharel, Madan K., Zhu, Lili L., van Lanen, Steven G., Rohr, Jürgen

Journal:

Organic & Biomolecular Chemistry

Year:

2010

Language:

english

File:

PDF, 259 KB

english, 2010

31

Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S -Adenosyl- L -Methionine Analogues

Singh, Shanteri, Zhang, Jianjun, Huber, Tyler D., Sunkara, Manjula, Hurley, Katherine, Goff, Randal D., Wang, Guojun, Zhang, Wen, Liu, Chunming, Rohr, Jürgen, Van Lanen, Steven G., Morris, Andrew J.,

Journal:

Angewandte Chemie International Edition

Year:

2014

Language:

english

File:

PDF, 1002 KB

english, 2014

32

A Biocatalytic Approach to Capuramycin Analogues by Exploiting a Substrate Permissive N-Transacylase CapW

Liu, Xiaodong, Jin, Yuanyuan, Cai, Wenlong, Green, Keith, Goswami, Anwesha, Garneau-Tsodikova, Sylvie, Nonaka, Koichi, Baba, Satashi, Funabashi, Masanori, Yang, Zhaoyong, Van Lanen, Steven

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 1.46 MB

english, 2016

33

Antibacterial and Cytotoxic Actinomycins Y 6 –Y 9 and Zp from Streptomyces sp. Strain Gö-GS12

Cai, Wenlong, Wang, Xiachang, Elshahawi, Sherif I., Ponomareva, Larissa V., Liu, Xiaodong, McErlean, Matthew R., Cui, Zheng, Arlinghaus, Ashley L., Thorson, Jon S., Van Lanen, Steven G.

Journal:

Journal of Natural Products

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

34

Characterization of a dual specificity aryl acid adenylation enzyme with dual function in nikkomycin biosynthesis

Mary Moon, Steven G. Van Lanen

Journal:

Year:

2010

Language:

english

File:

PDF, 681 KB

english, 2010

35

Cooperation of Two Bifunctional Enzymes in the Biosynthesis and Attachment of Deoxysugars of the Antitumor Antibiotic Mithramycin

Dr. Guojun Wang, Dr. Pallab Pahari, Dr. Madan K. Kharel, Dr. Jing Chen, Prof. Dr. Haining Zhu, Prof. Dr. Steven G. Van Lanen, Prof. Dr. Jürgen Rohr

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 672 KB

english, 2012

36

Roles of the Synergistic Reductive O -Methyltransferase GilM and of O -Methyltransferase GilMT in the Gilvocarcin Biosynthetic Pathway

Tibrewal, Nidhi, Downey, Theresa E., Van Lanen, Steven G., Ul Sharif, Ehesan, O’Doherty, George A., Rohr, Jürgen

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 647 KB

english, 2012

37

ChemInform Abstract: Enzymatic Strategies and Biocatalysts for Amide Bond Formation: Tricks of the Trade Outside of the Ribosome

Goswami, Anwesha, Van Lanen, Steven G.

Journal:

Year:

2016

File:

PDF, 16 KB

2016

38

Characterization of the Two-Component, FAD-Dependent Monooxygenase SgcC That Requires Carrier Protein-Tethered Substrates for the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027

Lin, Shuangjun, Van Lanen, Steven G., Shen, Ben

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 175 KB

english, 2008

39

Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics

Cui, Zheng, Liu, Xiaodong, Overbay, Jonathan, Cai, Wenlong, Wang, Xiachang, Lemke, Anke, Wiegmann, Daniel, Niro, Giuliana, Thorson, Jon S., Ducho, Christian, Van Lanen, Steven G.

Journal:

Journal of Organic Chemistry

Year:

2018

Language:

english

File:

PDF, 611 KB

english, 2018

40

Zusammenwirken zweier difunktionaler Enzyme bei Aufbau und Verknüpfung von Desoxyzuckern des Antitumor-Antibiotikums Mithramycin

Dr. Guojun Wang, Dr. Pallab Pahari, Dr. Madan K. Kharel, Dr. Jing Chen, Prof. Dr. Haining Zhu, Prof. Dr. Steven G. Van Lanen, Prof. Dr. Jürgen Rohr

Journal:

Angewandte Chemie

Year:

2012

Language:

german

File:

PDF, 470 KB

german, 2012

41

Characterization of the Maduropeptin Biosynthetic Gene Cluster from Actinomadura madurae ATCC 39144 Supporting a Unifying Paradigm for Enediyne Biosynthesis

Van Lanen, Steven G., Oh, Tae-jin, Liu, Wen, Wendt-Pienkowski, Evelyn, Shen, Ben

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 372 KB

english, 2007

42

Pyridoxal-5′-phosphate as an oxygenase cofactor: Discovery of a carboxamide-forming, α-amino acid monooxygenase-decarboxylase

Huang, Ying, Liu, Xiaodong, Cui, Zheng, Wiegmann, Daniel, Niro, Giuliana, Ducho, Christian, Song, Yuan, Yang, Zhaoyong, Van Lanen, Steven G.

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 980 KB

english, 2018

43

The Role of Tandem Acyl Carrier Protein Domains in Polyunsaturated Fatty Acid Biosynthesis

Jiang, Hui, Zirkle, Ross, Metz, James G., Braun, Lisa, Richter, Leslie, Van Lanen, Steven G., Shen, Ben

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 259 KB

english, 2008

44

Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics

Koppermann, Stefan, Cui, Zheng, Fischer, Patrick D., Wang, Xiachang, Ludwig, Jannine, Thorson, Jon S., Van Lanen, Steven G., Ducho, Christian

Journal:

Year:

2018

Language:

english

File:

PDF, 1.48 MB

english, 2018

45

A Theranostic Gallium Siderophore Ciprofloxacin Conjugate with Broad Spectrum Antibiotic Potency.

Pandey, Apurva, Savino, Chloe, Ahn, Shin Hye, Yang, Zhaoyong, Van Lanen, Steven G., Boros, Eszter

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 3.24 MB

english, 2019

46

Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin

Ute Galm, Martin H. Hager, Steven G. van Lanen, Jianhua Ju, Jon S. Thorson, Ben Shen

Journal:

Year:

2005

File:

PDF, 8 KB

2005

47

The Structure of l -Tyrosine 2,3-Aminomutase from the C-1027 Enediyne Antitumor Antibiotic Biosynthetic Pathway †,‡

Christianson, Carl V., Montavon, Timothy J., Van Lanen, Steven G., Shen, Ben, Bruner, Steven D.

Journal:

Year:

2007

Language:

english

File:

PDF, 1.29 MB

english, 2007

48

Functional AdoMet isosteres resistant to classical AdoMet degradation pathways

Huber, Tyler D., Wang, Fengbin, Singh, Shanteri, Johnson, Brooke R., Zhang, Jianjun, Sunkara, Manjula, Van Lanen, Steven G., Morris, Andrew J., Phillips, George N., Thorson, Jon S

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 1.62 MB

english, 2016

49

Macrolide derivatives reduce proinflammatory macrophage activation and macrophage-mediated neurotoxicity

Zhang, Bei, Kopper, Timothy J., Liu, Xiaodong, Cui, Zheng, Van Lanen, Steven G., Gensel, John C.

Journal:

CNS Neuroscience & Therapeutics

Year:

2019

File:

PDF, 1.40 MB

2019

50

Enzymatic Total Synthesis of Defucogilvocarcin M and Its Implications for Gilvocarcin Biosynthesis

Dr. Pallab Pahari, Prof. Dr. Madan K. Kharel, Dr. Micah D. Shepherd, Prof. Dr. Steven G. van Lanen, Prof. Dr. Jürgen Rohr

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 350 KB

english, 2012

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